The usual stories you read in the newspaper about brain damage discuss the person's change of personality and the burden on the spouse or other carer. Sometimes a story will focus on the "oddity" aspect: such as the SMH story on the man with an uncontrollable sex drive after an accident.
Richard Powers' The Echo Maker focuses on a man who cannot recognise his sister after an accident and his search for his memory, starting with the cause of his accident. Along the way we meet his sister, a neurologist author and the cranes who come to Nebraska each year.
This is a compelling story which shows the frustrations of all involved: the victim, the family, the doctors, the friends. There is a satisfactory resolution but not necessarily on all levels.
New York Review of Books' review by Margaret Atwood.